| Dec'19 | Dec'18 | Dec'17 | ||||
|---|---|---|---|---|---|---|
Collaboration revenue | ||||||
7,804 | 1,420 | - | ||||
Operating expenses: | ||||||
Research and development | ||||||
76,369 | 58,024 | 47,023 | ||||
General and administrative | ||||||
28,632 | 22,606 | 14,311 | ||||
Change in fair value of contingent consideration | ||||||
13 | 25,020 | 17,914 | ||||
Impairment of intangible asset | ||||||
18,559 | - | - | ||||
Total operating expenses | ||||||
123,573 | 105,650 | 79,248 | ||||
Loss from operations | ||||||
-115,769 | -104,230 | -79,248 | ||||
Other income (expense): | ||||||
Interest income, net | ||||||
2,010 | 1,323 | 281 | ||||
Other expense | ||||||
-20 | -53 | 43 | ||||
Total other income (expense), net | ||||||
1,990 | 1,270 | 324 | ||||
Loss before benefit from income taxes | ||||||
-113,779 | -102,960 | -78,924 | ||||
Benefit from income taxes | ||||||
-486 | -5,565 | -12,481 | ||||
Net loss | ||||||
-113,293 | -97,395 | -66,443 | ||||
Accretion of redeemable convertible preferred stock to redemption value | ||||||
- | 644 | 719 | ||||
Net loss attributable to common stockholders | ||||||
-113,293 | -98,039 | -67,162 | ||||
Net loss per share—basic and diluted | ||||||
-2.20 | -3.64 | -8.66 | ||||
Weighted average common shares outstanding—basic and diluted | ||||||
51,445 | 26,945 | 7,756 | ||||