| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 |
|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||
Net loss | ||||||
-22,674 | -34,959 | -19,103 | -27,008 | - | - | - |
Net loss | ||||||
- | - | - | - | -24,410 | -6,809 | -7,708 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||
Stock-based compensation | ||||||
1,624 | 2,667 | 3,194 | 3,083 | 2,088 | 271 | 275 |
Common stock issued for services | ||||||
- | - | 29 | 23 | - | - | - |
Depreciation and amortization | ||||||
22 | 28 | 48 | 94 | 51 | 15 | 7 |
Noncash interest | ||||||
234 | 272 | 354 | 522 | 417 | 300 | 22 |
Amortization of debt discount | ||||||
81 | 94 | 117 | 100 | 97 | 99 | 4 |
Amortization of premium/discount on short-term investments | ||||||
52 | 100 | 9 | -3 | -8 | - | - |
Lease asset amortization and liability accretion, net | ||||||
-6 | - | - | - | - | - | - |
Change in fair value of preferred stock warrant liability | ||||||
- | - | - | - | 65 | -37 | 34 |
Change in fair value of preferred stock purchase rights | ||||||
- | - | - | - | - | - | 84 |
Deferred rent | ||||||
- | 11 | 60 | -53 | -4 | 45 | 8 |
Deferred revenue | ||||||
- | -3,000 | 1,741 | -2,094 | - | - | - |
Deferred revenue | ||||||
- | - | - | - | -3,550 | 6,903 | - |
Changes in assets and liabilities: | ||||||
Prepaid expenses and other assets | ||||||
-651 | -92 | 356 | 42 | 424 | 1,701 | -9 |
Accounts payable and accrued expenses | ||||||
-3,421 | 4,142 | 776 | -2,203 | 6,144 | 2,282 | - |
Accounts payable and accrued expenses | ||||||
- | - | - | - | - | - | 443 |
Accrued compensation and related expenses | ||||||
-109 | -30 | -94 | 425 | 355 | 390 | 152 |
Net cash used in operating activities | ||||||
-23,650 | -30,783 | -13,243 | -27,150 | - | - | - |
Cash flows from investing activities | ||||||
Net cash used in operating activities | ||||||
- | - | - | - | -19,163 | 1,758 | -6,670 |
Purchase of property and equipment | ||||||
- | - | 39 | 3 | 127 | 70 | 7 |
Purchases of available-for-sale short-term investments | ||||||
4,980 | 32,869 | 13,992 | 17,506 | - | - | - |
Purchases of available-for-sale short-term investments | ||||||
- | - | - | - | 12,790 | - | - |
Proceeds from the maturity of available-for-sale short-term investments | ||||||
19,000 | 24,000 | 17,705 | 19,582 | 2,000 | - | - |
Net cash provided by investing activities | ||||||
14,020 | -8,869 | 3,674 | 2,073 | - | - | - |
Cash flows from financing activities | ||||||
Net cash provided by investing activities | ||||||
- | - | - | - | -10,917 | -70 | -7 |
Proceeds from long-term debt | ||||||
- | 7,000 | 8,000 | - | 10,000 | 7,500 | 2,500 |
Repayment of long-term debt | ||||||
1,400 | 8,320 | 8,850 | 2,000 | 9,930 | 920 | - |
Proceeds from sale of common stock and warrants, net of offering costs | ||||||
2,294 | 36,456 | 4,141 | 21,236 | - | - | - |
Proceeds from sale of common stock, net of offering costs paid in the current period | ||||||
- | - | - | - | 36,204 | -1,250 | - |
Proceeds from sale of preferred stock, net of offering costs | ||||||
- | - | - | - | - | 25,654 | 3,994 |
Proceeds from issuance of common stock under equity plans | ||||||
32 | 263 | 172 | 178 | 179 | 52 | - |
Payment of tax withholdings related to net share settlements of vested restricted stock awards | ||||||
20 | 78 | 137 | - | - | - | - |
Net cash provided by (used in) financing activities | ||||||
906 | 35,321 | 3,326 | 19,414 | - | - | - |
Decrease in cash and cash equivalents | ||||||
-8,724 | -4,331 | -6,243 | - | - | - | - |
Net cash provided by (used in) financing activities | ||||||
- | - | - | - | 36,453 | 31,036 | 6,494 |
Increase in cash and cash equivalents | ||||||
- | - | - | -5,663 | 6,373 | 32,724 | -183 |
Supplemental disclosure of cash flow information | ||||||
Interest paid | ||||||
612 | 642 | 664 | 622 | 428 | 270 | 4 |
Supplemental schedule of noncash investing and financing activities | ||||||
Issuance of preferred stock warrants in connection with long-term debt | ||||||
- | - | - | - | - | 186 | 63 |
Issuance of common stock warrants in connection with long-term debt | ||||||
- | 98 | 174 | - | 138 | - | - |
Issuance of common stock in connection with common stock purchase agreement | ||||||
450 | - | 793 | - | - | - | - |