| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||||||||||||||||
Net loss | ||||||||||||||||||||
-4,021 | -3,936 | -5,199 | -6,326 | -7,213 | -7,756 | -9,085 | -9,754 | -8,364 | - | - | - | - | - | - | - | - | - | - | - | - |
Net loss | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | -6,566 | -7,147 | - | -5,871 | -8,297 | -6,526 | -11,047 | -6,447 | -2,921 | -3,995 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||||||||||||
Stock-based compensation | ||||||||||||||||||||
267 | 297 | 315 | 416 | 596 | 623 | 674 | 664 | 706 | 796 | 797 | 795 | 806 | 744 | 539 | 943 | 857 | 742 | 672 | 427 | 247 |
Common stock issued for services | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | 0 | 6 | 10 | 13 | - | - | - | - | - | - | - | - |
Depreciation and amortization | ||||||||||||||||||||
4 | 4 | 5 | 6 | 7 | 7 | 7 | 7 | 7 | 7 | 7 | 11 | 23 | 24 | 22 | 24 | 24 | 18 | 15 | 10 | 8 |
Noncash interest | ||||||||||||||||||||
46 | 52 | 59 | 62 | 61 | 63 | 63 | 67 | 79 | 87 | 87 | 86 | 94 | 119 | 132 | 136 | 135 | 94 | 91 | 106 | 126 |
Amortization of debt discount | ||||||||||||||||||||
16 | 18 | 20 | 22 | 21 | 22 | 21 | 24 | 27 | 31 | 30 | 29 | 27 | 23 | 25 | 26 | 26 | 19 | 18 | 26 | 34 |
Amortization of premium/discount on short-term investments | ||||||||||||||||||||
- | 0 | 0 | 16 | 36 | 44 | 45 | 10 | 1 | 3 | 2 | 3 | 1 | 1 | -1 | -1 | -2 | - | - | - | - |
Lease asset amortization and liability accretion, net | ||||||||||||||||||||
-3 | - | - | - | 2 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Change in fair value of preferred stock warrant liability | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 65 |
Deferred rent | ||||||||||||||||||||
- | - | - | - | - | 1 | 1 | 2 | 7 | 6 | 38 | 32 | -16 | -15 | -13 | -13 | -12 | 0 | -9 | 13 | -8 |
Deferred revenue | ||||||||||||||||||||
- | - | - | - | - | 0 | 0 | 0 | -3,000 | - | - | - | - | - | - | - | - | - | - | - | - |
Deferred revenue | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | -485 | -388 | - | -437 | -203 | -964 | -968 | -868 | -909 | -805 |
Changes in assets and liabilities: | ||||||||||||||||||||
Prepaid expenses and other assets | ||||||||||||||||||||
-139 | -369 | 623 | -425 | -480 | 231 | -226 | 192 | -289 | 150 | 627 | -312 | -109 | -86 | -292 | 265 | 155 | -1,063 | -2,112 | 2,637 | 962 |
Accounts payable and accrued expenses | ||||||||||||||||||||
-979 | -1,343 | -1,276 | -583 | -219 | -1,119 | 1,578 | -73 | 3,756 | 308 | -10 | 907 | -429 | -584 | 58 | -2,000 | 323 | 2,365 | 611 | 2,326 | 842 |
Accrued compensation and related expenses | ||||||||||||||||||||
-761 | 299 | 119 | 223 | -750 | 308 | 335 | -912 | 239 | 169 | 229 | 164 | -656 | 400 | 209 | 194 | -378 | 190 | 270 | 247 | -352 |
Net cash used in operating activities | ||||||||||||||||||||
-5,292 | -4,243 | -6,583 | -5,773 | -7,051 | -8,126 | -6,225 | -10,177 | -6,255 | - | - | - | - | - | - | - | - | - | - | - | - |
Cash flows from investing activities | ||||||||||||||||||||
Net cash used in operating activities | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | -7,565 | - | -5,043 | -9,454 | -6,668 | -7,518 | -3,533 | -3,312 | -4,800 |
Purchase of property and equipment | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | 9 | 6 | 18 | 6 | 0 | 0 | 0 | 3 | 50 | 13 | 62 | 2 |
Purchases of available-for-sale short-term investments | ||||||||||||||||||||
- | 0 | 0 | 0 | 4,980 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Purchases of available-for-sale short-term investments | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 0 | 5,995 | 2,999 | - | 5,220 | 2,137 | 1,445 | - | - | - | - |
Proceeds from the maturity of available-for-sale short-term investments | ||||||||||||||||||||
- | 0 | 0 | 10,000 | 9,000 | 19,000 | 0 | 0 | 5,000 | 3,000 | 3,000 | 4,500 | 7,205 | 5,465 | 1,891 | 2,225 | 10,001 | - | - | - | - |
Net cash provided by investing activities | ||||||||||||||||||||
- | 0 | 0 | 10,000 | 4,020 | 5,054 | 0 | -18,923 | 5,000 | - | - | - | - | - | - | - | - | - | - | - | - |
Cash flows from financing activities | ||||||||||||||||||||
Net cash provided by investing activities | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 4,200 | - | -3,329 | 88 | 8,553 | -335 | -10,518 | -62 | -2 |
Proceeds from long-term debt | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 8,000 | - | - | - | - | - | - | - | - |
Repayment of long-term debt | ||||||||||||||||||||
700 | - | - | - | - | 0 | 0 | 7,520 | 800 | 0 | 0 | 0 | 8,850 | - | - | - | - | 0 | 0 | 8,753 | 1,177 |
Proceeds from sale of common stock and warrants, net of offering costs | ||||||||||||||||||||
- | - | - | - | - | -24 | -27 | 1,348 | 35,159 | - | - | - | - | - | - | - | - | - | - | - | - |
Proceeds from sale of common stock and warrants | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 2,610 | 0 | 1,000 | - | - | - | - | - | - | - | - |
Proceeds from sale of common stock, net of offering costs | ||||||||||||||||||||
3,720 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | -3 | 0 | 36,263 |
Costs paid in connection with sales of common stock | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 80 | 91 | 168 | - | - | - | - | - | - | - | - |
Proceeds from issuance of common stock under equity plans | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | 49 | 0 | 92 | 31 | 50 | 0 | 121 | 7 | 130 | 42 | 0 | 7 |
Payment of tax withholdings related to net share settlements of vested restricted stock awards | ||||||||||||||||||||
6 | 0 | 0 | 0 | 20 | 0 | 0 | 0 | 78 | 0 | 0 | 0 | 137 | - | - | - | - | - | - | - | - |
Net cash provided by (used in) financing activities | ||||||||||||||||||||
3,014 | 1,602 | -700 | 24 | -20 | 15 | -16 | 1,041 | 34,281 | - | - | - | - | - | - | - | - | - | - | - | - |
Decrease in cash and cash equivalents | ||||||||||||||||||||
-2,278 | - | - | - | -3,051 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Net cash provided by (used in) financing activities | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | -124 | - | 4,000 | 121 | 7 | 2,074 | 39 | -753 | 35,093 |
Increase in cash and cash equivalents | ||||||||||||||||||||
- | - | - | - | - | - | - | -28,059 | 33,026 | - | 6,863 | -6,220 | -3,489 | 6,062 | -4,372 | -9,245 | 1,892 | -5,779 | -14,012 | -4,127 | 30,291 |