| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
License revenue | ||||||||||||||||
- | 9 | 9 | 9 | 9 | 9 | 18,009 | 9 | 9 | - | 10 | 10 | - | - | - | - | - |
License revenue | ||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 11 | - | 11 | 13 | 14 |
Operating expenses: | ||||||||||||||||
Research and development | ||||||||||||||||
3,141 | 7,596 | 13,295 | 11,974 | 12,434 | 15,619 | 12,262 | 12,763 | 10,436 | 8,294 | 7,563 | 6,632 | 6,624 | 6,633 | 7,586 | 6,530 | 6,469 |
General and administrative | ||||||||||||||||
5,556 | 3,115 | 3,837 | 4,850 | 4,446 | 3,497 | 4,320 | 2,573 | 2,419 | 2,402 | 2,184 | 2,030 | 1,940 | 1,351 | 956 | 1,103 | 1,111 |
Total operating expenses | ||||||||||||||||
8,697 | 10,711 | 17,132 | 16,824 | 16,880 | 19,116 | 16,582 | 15,336 | 12,855 | 10,696 | 9,747 | 8,662 | 8,564 | 7,984 | 8,542 | 7,633 | 7,580 |
Loss from operations | ||||||||||||||||
-8,697 | -10,702 | -17,123 | -16,815 | -16,871 | -19,107 | 1,427 | -15,327 | -12,846 | -10,686 | -9,737 | -8,652 | -8,553 | -7,973 | -8,531 | -7,620 | -7,566 |
Other income (expense), net: | ||||||||||||||||
Interest income | ||||||||||||||||
58 | 197 | 361 | 465 | 541 | 447 | 441 | 331 | 315 | 241 | 214 | 103 | 37 | 45 | 53 | 56 | 61 |
Interest expense | ||||||||||||||||
756 | 329 | 1,973 | 764 | 754 | 746 | 742 | 1,093 | 349 | 391 | 430 | 495 | 616 | 533 | 511 | 505 | 503 |
Loss on disposal of assets | ||||||||||||||||
-885 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Total other expense, net | ||||||||||||||||
-1,583 | - | -1,612 | -299 | -213 | - | -301 | -762 | -34 | - | - | - | - | - | - | - | - |
Change in fair value of preferred stock warrants | ||||||||||||||||
- | - | - | - | - | - | - | - | - | 0 | 0 | 22 | -59 | -32 | 11 | -27 | -2 |
Loss before income taxes | ||||||||||||||||
- | - | -18,735 | - | - | - | 1,126 | - | - | - | -9,953 | - | - | - | - | - | - |
Income tax expense | ||||||||||||||||
- | - | - | - | - | - | 1,509 | - | - | - | - | - | - | - | - | - | - |
Total other expense, net | ||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | -414 | -520 | - | -469 | -422 | -440 |
Net loss | ||||||||||||||||
-10,280 | -10,583 | -18,735 | -17,114 | -17,084 | -19,603 | -383 | -16,089 | -12,880 | -10,837 | -9,953 | -9,066 | -9,073 | -8,430 | -9,000 | -8,042 | -8,006 |
Other comprehensive income (loss): | ||||||||||||||||
Net unrealized (loss) gain on investments | ||||||||||||||||
-10 | -33 | -13 | 38 | 41 | 0 | 31 | 54 | -74 | -31 | 4 | -6 | -1 | -9 | 0 | 13 | 54 |
Comprehensive loss | ||||||||||||||||
-10,290 | -10,616 | -18,748 | -17,076 | -17,043 | -19,603 | -352 | -16,035 | -12,954 | -10,868 | -9,949 | -9,072 | -9,074 | -8,439 | -9,000 | -8,029 | -7,952 |
Net loss per common share, basic and diluted | ||||||||||||||||
-0.43 | -0.45 | -0.78 | -0.72 | -0.74 | -0.96 | -0.02 | -0.81 | -0.65 | 2.51 | -0.50 | -0.56 | -4.11 | -3.83 | -4.09 | -3.66 | -3.64 |
Weighted-average number of common shares outstanding, basic and diluted | ||||||||||||||||
23,902 | 23,910 | 23,897 | 23,673 | 23,040 | 20,458 | 19,951 | 19,922 | 19,905 | 20,082 | 19,809 | 16,330 | 2,207 | 2,202 | 2,200 | 2,198 | 2,198 |