| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 |
|---|---|---|---|---|---|---|---|---|
Revenues: | ||||||||
Total revenue | ||||||||
7,376 | 18,904 | 9,666 | - | - | - | - | - | - |
Expenses: | ||||||||
Total revenues | ||||||||
- | - | - | 5,145 | 11,686 | 9,098 | 10,486 | 7,600 | 185 |
Research and development | ||||||||
22,785 | 54,879 | 101,706 | 63,764 | 73,768 | 61,932 | 31,508 | 17,294 | 17,737 |
Selling, general and administrative | ||||||||
49,043 | 37,078 | 23,675 | - | - | - | - | - | - |
Total expenses | ||||||||
74,908 | 92,185 | 125,381 | - | - | - | - | - | - |
General and administrative | ||||||||
- | - | - | 19,211 | 20,916 | 12,932 | 7,168 | 4,309 | 3,874 |
Total operating expenses | ||||||||
- | - | - | 82,975 | 94,684 | 74,864 | 38,676 | 21,603 | 21,611 |
Loss from operations | ||||||||
-67,532 | -73,281 | -115,715 | -77,830 | -82,998 | -65,766 | -28,190 | -14,003 | -21,426 |
Other income and expenses | ||||||||
Loss on extinguishment of debt | ||||||||
-1,568 | - | - | - | - | - | - | - | - |
Other income | ||||||||
333 | - | - | - | - | - | - | - | - |
Interest income | ||||||||
1,262 | 1,747 | 963 | - | - | 17 | 10 | - | 1 |
Interest expense | ||||||||
2,580 | 624 | - | - | - | 1,017 | 1,719 | 1,021 | 161 |
Other income (expense) | ||||||||
- | - | - | 350 | -191 | 24 | 263 | -63 | 22 |
Other income (expense), net | ||||||||
- | - | - | 350 | -191 | -976 | -1,446 | -1,084 | -138 |
Net loss | ||||||||
-70,085 | -72,158 | -114,752 | -77,480 | -83,189 | -66,742 | -29,636 | -15,087 | -21,564 |
Net loss per share-basic and diluted | ||||||||
-22.85 | -27.48 | -2.63 | -2.11 | -2.36 | -2.49 | -1.78 | -47.54 | -73.34 |
Weighted-average number of common shares used in net loss per share-basic and diluted | ||||||||
3,067 | 2,626 | 43,582 | 36,704 | 35,261 | 26,807 | 16,665 | 317 | 294 |
Comprehensive loss | ||||||||
-70,085 | -72,158 | -114,752 | -77,480 | -83,189 | -66,742 | -29,636 | -15,087 | -21,564 |
Product Revenue, net [Member] | ||||||||
Total revenue | ||||||||
3,575 | 178 | - | - | - | - | - | - | - |
Cost of revenue | ||||||||
2,687 | 130 | - | - | - | - | - | - | - |
License and Collaboration Revenue [Member] | ||||||||
Total revenue | ||||||||
2,000 | 12,677 | - | - | - | - | - | - | - |
Government Revenue [Member] | ||||||||
Total revenue | ||||||||
1,801 | 6,049 | 9,666 | - | - | - | - | - | - |
Intangible asset amortization [Member] | ||||||||
Cost of revenue | ||||||||
393 | 98 | - | - | - | - | - | - | - |