| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|
Operating activities | ||||||||||||
Net loss | ||||||||||||
-28,038 | -18,027 | -21,710 | -23,673 | -18,767 | -21,916 | -18,347 | -20,002 | -16,133 | -12,543 | -11,751 | -11,428 | -8,934 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||||
Depreciation and amortization | ||||||||||||
903 | 745 | 638 | 643 | 637 | 596 | 561 | 521 | 502 | 468 | 448 | 294 | 94 |
Net accretion and amortization of premium and discounts on marketable securities | ||||||||||||
63 | 116 | 269 | 400 | 366 | 369 | 383 | 170 | 33 | - | - | - | - |
Amortization of premium and discounts on marketable securities | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 13 |
Stock-based compensation | ||||||||||||
3,317 | 3,088 | 3,823 | 1,944 | 1,997 | 2,516 | 2,717 | 2,838 | 1,370 | 1,537 | 559 | 525 | 413 |
Non-cash rent expense | ||||||||||||
461 | - | - | - | 400 | - | - | - | - | - | - | - | - |
Impairment of long-lived assets | ||||||||||||
2,159 | - | - | - | - | - | - | - | - | - | - | - | - |
Change in fair value of strategic investment | ||||||||||||
-1,387 | - | - | - | - | - | - | - | - | - | - | - | - |
Accretion of tenant improvement allowance | ||||||||||||
- | 402 | 403 | 318 | 152 | 149 | 151 | 153 | 152 | 152 | 151 | 151 | 151 |
Change in fair value of contingent consideration | ||||||||||||
-221 | - | - | - | -1,245 | - | - | - | - | - | - | - | - |
Changes in operating assets and liabilities: | ||||||||||||
Contribution receivable | ||||||||||||
- | - | - | - | - | 0 | 0 | 0 | -1,382 | - | - | - | - |
Prepaid expenses and other current assets | ||||||||||||
-123 | -250 | -347 | 954 | -188 | -173 | 353 | 953 | -291 | -52 | 285 | 194 | 319 |
Other long-term assets | ||||||||||||
-29 | 6 | 8 | 8 | 9 | -502 | 7 | 1,095 | 4 | 1 | 1 | 1 | -26 |
Accounts payable | ||||||||||||
-1,345 | 104 | -722 | 1,167 | -776 | 2,137 | 724 | -2,463 | 1,830 | -2,254 | 1,654 | 753 | 1,045 |
Accrued compensation | ||||||||||||
-3,675 | 2,233 | 931 | 1,067 | -2,117 | 952 | 898 | 983 | -1,223 | - | - | - | - |
Accrued compensation | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | -190 |
Accrued and other current liabilities | ||||||||||||
-110 | -85 | 529 | -1,096 | 65 | 606 | -130 | 731 | 239 | 1,771 | -287 | -160 | -66 |
Deferred rent, net of current portion | ||||||||||||
- | 1,057 | 1,125 | 330 | -51 | -48 | -49 | -44 | 48 | - | - | - | - |
Deferred rent, net of current portion | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | 54 | 209 |
Net cash used in operating activities | ||||||||||||
-25,073 | -15,691 | -16,833 | -19,301 | -20,596 | -12,806 | -13,885 | -18,049 | -11,883 | -11,600 | -9,121 | -9,777 | -7,860 |
Investing activities | ||||||||||||
Purchase of marketable securities | ||||||||||||
36,950 | 29,112 | 39,459 | 32,645 | 18,054 | 38,016 | 28,267 | 131,578 | 6,225 | 14,170 | 10,010 | 51,071 | 59,214 |
Maturities of marketable securities | ||||||||||||
40,650 | 25,249 | 65,080 | 40,159 | 58,321 | 37,975 | 37,185 | 39,211 | 19,273 | - | - | - | - |
Purchase of property and equipment | ||||||||||||
34 | 609 | 540 | 230 | 207 | 448 | 290 | 425 | 101 | 326 | 379 | 690 | 294 |
Net cash provided by investing activities | ||||||||||||
3,666 | -4,472 | 25,081 | 7,284 | 40,060 | -989 | 8,628 | -92,792 | 12,947 | 8,943 | 11,271 | -47,011 | -59,508 |
Financing activities | ||||||||||||
Proceeds from issuance of common stock under ATM Offering Program, net of issuance costs | ||||||||||||
8,763 | - | - | - | - | - | - | - | - | - | - | - | - |
Proceeds from issuance of convertible preferred stock, net of issuance costs | ||||||||||||
- | - | - | - | - | -18 | 0 | 4,948 | 54,951 | -1 | -12 | 34,896 | 7,984 |
Proceeds from issuance of common stock upon exercise of stock options, net of repurchases | ||||||||||||
249 | - | - | - | 300 | - | - | - | 27 | - | - | - | - |
Other financing cash flows | ||||||||||||
-19 | - | - | - | -18 | - | - | - | - | - | - | - | - |
Proceeds from issuance of common stock upon exercise of stock options, net of repurchases | ||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | 2 |
Payment of initial public offering costs | ||||||||||||
- | - | - | - | - | 0 | 2 | 2,630 | 569 | - | - | - | - |
Payments made on capital lease obligations | ||||||||||||
- | - | - | - | - | 22 | 18 | 17 | 17 | - | - | - | - |
Net cash provided by financing activities | ||||||||||||
8,993 | 20,868 | 5,407 | 881 | 282 | 297 | -11 | 82,252 | 54,392 | -12 | -87 | 34,888 | 7,986 |
Net increase (decrease) in cash, cash equivalents and restricted cash | ||||||||||||
-12,414 | 705 | 13,655 | -11,136 | 19,746 | - | - | - | - | - | - | - | - |
Net increase in cash, cash equivalents and restricted cash | ||||||||||||
- | - | - | - | - | - | - | - | 55,456 | - | 2,063 | -21,900 | -59,382 |
Supplemental Disclosures of Non-Cash Investing and Financing Activities | ||||||||||||
Property and equipment included in accounts payable and accrued liabilities | ||||||||||||
302 | 503 | 15 | -24 | 71 | 86 | 17 | 104 | 34 | 11 | -225 | 402 | 126 |
Issuance of shares in settlement of share-based liability | ||||||||||||
100 | - | - | - | - | - | - | - | - | - | - | - | - |
Issuance of common stock to settle contingent consideration liability | ||||||||||||
- | - | - | - | 2,059 | - | - | - | - | - | - | - | - |
Deferred offering costs included in accounts payable and accrued liabilities | ||||||||||||
- | - | - | - | - | - | - | - | 1,138 | - | - | - | - |
Receipt of promissory note from related party for purchase of common stock | ||||||||||||
- | - | - | - | - | 0 | 0 | 0 | 390 | - | - | - | - |
Receipt of promissory note from employees for purchase of common stock | ||||||||||||
- | - | - | - | - | - | 0 | 0 | 400 | - | - | - | - |