| Dec'19 | Dec'18 | Dec'17 | Dec'16 | |||
|---|---|---|---|---|---|---|
Contribution revenue | ||||||
- | - | 1,382 | - | |||
Operating expenses: | ||||||
Research and development | ||||||
70,957 | 58,907 | 37,373 | 13,707 | |||
General and administrative | ||||||
20,046 | 16,016 | 9,617 | 5,137 | |||
Change in fair value of contingent consideration | ||||||
-1,352 | 4,542 | - | - | |||
Total operating expenses | ||||||
89,651 | 79,465 | 46,990 | 18,844 | |||
Loss from operations | ||||||
-89,651 | -79,465 | -45,608 | -18,844 | |||
Loss on extinguishment of promissory notes | ||||||
- | - | - | -9,377 | |||
Interest income | ||||||
3,289 | 3,312 | 1,055 | -2,183 | |||
Other expense, net | ||||||
4,185 | -245 | -103 | - | |||
Net loss | ||||||
-82,177 | -76,398 | -44,656 | -30,404 | |||
Other comprehensive loss | ||||||
Unrealized gain on marketable debt securities, net of tax | ||||||
185 | 9 | -104 | - | |||
Comprehensive loss | ||||||
-81,992 | -76,389 | -44,760 | -30,404 | |||
Net loss per share, basic and diluted | ||||||
-1.88 | -2.70 | -13.97 | -11.42 | |||
Weighted average number of shares used in computing net loss per share, basic and diluted | ||||||
43,624 | 28,269 | 3,197 | 2,662 | |||