| Dec'19 | Dec'18 | Dec'17 | Dec'16 | Dec'15 | Dec'14 | Dec'13 | Dec'12 | Dec'11 |
|---|---|---|---|---|---|---|---|---|
Revenue: | ||||||||
Total revenue | ||||||||
17,456 | 26,718 | - | - | - | - | - | - | - |
Operating expenses: | ||||||||
Cost of sales - product | ||||||||
1,238 | 165 | - | - | - | - | - | - | - |
Cost of sales - intangible amortization | ||||||||
1,569 | 423 | - | - | - | - | - | - | - |
Research and development | ||||||||
45,778 | 43,648 | 46,423 | 19,779 | 40,565 | 35,448 | 25,930 | 21,712 | 9,883 |
Selling, general and administrative | ||||||||
101,212 | 77,265 | 21,381 | 17,223 | - | - | - | - | - |
Total operating expenses | ||||||||
149,797 | 121,501 | 67,804 | - | - | - | - | - | - |
General and administrative | ||||||||
- | - | - | - | 17,634 | 18,159 | 15,472 | 10,518 | 3,815 |
Total operating expenses | ||||||||
- | - | - | 37,002 | 58,199 | 53,607 | 41,402 | 32,230 | 13,698 |
Loss from operations | ||||||||
-132,341 | -94,783 | -67,804 | -37,002 | -58,199 | -53,607 | -41,402 | -32,230 | -13,698 |
Other expense | ||||||||
-641 | 25,556 | - | - | - | - | - | - | - |
Interest income | ||||||||
4,381 | 2,603 | 561 | 562 | 334 | 242 | 200 | 246 | 15 |
Interest expense | ||||||||
20,608 | 5,810 | 559 | - | - | - | - | - | - |
Accretion of preferred stock | ||||||||
- | - | - | - | - | - | - | 6 | 32 |
Net loss | ||||||||
- | - | - | - | - | -53,365 | - | -31,990 | -13,715 |
Net loss | ||||||||
-149,209 | -72,434 | -67,802 | -36,440 | -57,865 | - | -41,202 | -31,984 | -13,683 |
Net loss per share—basic (in shares) | ||||||||
74,578 | 64,962 | 38,422 | 36,988 | - | - | - | - | - |
Net loss per share—diluted (in shares) | ||||||||
74,578 | 69,321 | 38,422 | 36,988 | - | - | - | - | - |
Net loss per share—basic and diluted | ||||||||
- | - | - | - | -1.61 | -2.07 | -1.82 | -1.70 | -10.59 |
Net loss per share—basic | ||||||||
-2.00 | -1.12 | -1.76 | -0.99 | - | - | - | - | - |
Net loss per share—diluted | ||||||||
-2.00 | -1.37 | -1.76 | -0.99 | - | - | - | - | - |
Weighted average common shares outstanding used in computing: | ||||||||
Weighted average common shares outstanding used in computing net loss per share - basic and diluted | ||||||||
- | - | - | - | 35,932 | 25,804 | 22,680 | 18,765 | 1,295 |
Net loss | ||||||||
- | - | - | - | - | -53,365 | - | -31,990 | -13,715 |
Net loss | ||||||||
-149,209 | -72,434 | -67,802 | -36,440 | -57,865 | - | -41,202 | -31,984 | -13,683 |
Unrealized (loss) gain on available-for-sale securities | ||||||||
-113 | 129 | -31 | -14 | 32 | -17 | 6 | 24 | -2 |
Comprehensive loss | ||||||||
-149,322 | -72,305 | -67,833 | -36,454 | -57,833 | -53,382 | -41,196 | -31,960 | -13,685 |
Product revenue, net | ||||||||
Total revenue | ||||||||
12,339 | 1,718 | - | - | - | - | - | - | - |
License and collaboration revenue | ||||||||
Total revenue | ||||||||
5,117 | 25,000 | - | - | - | - | - | - | - |