| Mar'20 | Dec'19 | Sep'19 | Jun'19 | Mar'19 | Dec'18 | Sep'18 | Jun'18 | Mar'18 | Dec'17 | Sep'17 | Jun'17 | Mar'17 | Dec'16 | Sep'16 | Jun'16 | Mar'16 | Dec'15 | Sep'15 | Jun'15 | Mar'15 |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Cash flows from operating activities | ||||||||||||||||||||
Net loss | ||||||||||||||||||||
-47,493 | -56,770 | -50,726 | -41,942 | -44,200 | -37,887 | -37,631 | -35,894 | -35,241 | -30,793 | -25,494 | -24,597 | -21,096 | -18,713 | -17,535 | -11,565 | -7,847 | -7,099 | -4,936 | -3,700 | -3,465 |
Adjustments to reconcile net loss to net cash used in operating activities: | ||||||||||||||||||||
Amortization of lease incentive obligation | ||||||||||||||||||||
- | - | - | - | - | 289 | 232 | 162 | 107 | 77 | 65 | 49 | 17 | - | - | - | - | - | - | - | - |
Amortization of right-of-use assets | ||||||||||||||||||||
442 | 426 | 411 | 395 | 381 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Depreciation of property and equipment | ||||||||||||||||||||
2,039 | 2,016 | 1,947 | 1,854 | 1,783 | 1,733 | 1,458 | 1,234 | 1,175 | 934 | 595 | 356 | 315 | 259 | 188 | 184 | 153 | 132 | 284 | 89 | 89 |
Share-based compensation expense | ||||||||||||||||||||
3,999 | 4,987 | 5,020 | 5,157 | 4,345 | 4,011 | 3,610 | 3,545 | 4,430 | 3,177 | 3,000 | 2,967 | 2,999 | 2,528 | 2,183 | 1,270 | 866 | 814 | 718 | 646 | 1,846 |
Net loss on disposal of property and equipment | ||||||||||||||||||||
- | - | - | - | - | 0 | 10 | -41 | -13 | - | - | - | - | - | - | - | - | - | - | - | - |
Deferred rent | ||||||||||||||||||||
- | - | - | - | - | 73 | 230 | 283 | 387 | 387 | 1,023 | 1,153 | 1,031 | 194 | 117 | 118 | 136 | 92 | -1 | 27 | -30 |
Deferred income taxes | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | 4 | 772 | 325 | -193 | -876 | 135 | 48 | -5 | -146 | 83 | 49 | 50 |
Changes in operating assets and liabilities: | ||||||||||||||||||||
Accounts receivable | ||||||||||||||||||||
-20,000 | - | - | - | - | 0 | -5,000 | 65,000 | -1,000 | - | - | - | - | - | - | - | - | - | 7 | -231 | 31 |
Prepaid expenses | ||||||||||||||||||||
373 | - | - | - | 1,090 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Prepaid expenses and other current assets | ||||||||||||||||||||
- | - | - | - | - | - | 1,429 | 3,773 | 485 | - | 1,544 | 530 | 1,813 | 871 | -1,603 | 1,655 | 414 | -170 | 22 | -32 | 50 |
Other assets | ||||||||||||||||||||
1,983 | - | - | - | 2,124 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Other non-current assets | ||||||||||||||||||||
- | - | - | - | - | - | 5 | -1 | 11 | - | - | - | - | - | - | - | 53 | - | - | - | - |
Accounts payable | ||||||||||||||||||||
7,336 | -10,968 | 8,431 | -1,743 | 783 | 2,135 | 3,113 | -702 | 390 | 3,268 | -1,061 | 668 | 1,017 | 1,470 | 716 | 1,479 | -296 | -816 | 751 | 1,464 | 249 |
Accrued expenses and other current liabilities | ||||||||||||||||||||
-5,191 | 2,446 | 2,106 | 3,363 | -6,467 | 5,217 | 1,416 | 1,772 | -2,541 | 2,652 | 1,734 | 701 | -537 | -188 | 1,276 | 879 | 329 | 340 | 282 | -104 | -251 |
Deferred revenue | ||||||||||||||||||||
-4,161 | -2,400 | -2,929 | -7,628 | -3,026 | -3,622 | -4,492 | 170,121 | -1,422 | -98 | -1,315 | -1,097 | -383 | - | - | - | - | 0 | 0 | -126 | -26 |
Operating lease liabilities | ||||||||||||||||||||
-765 | -750 | -712 | -691 | -663 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Other non-current liabilities | ||||||||||||||||||||
-100 | -72 | -104 | -142 | -103 | 647 | -38 | -72 | -14 | 598 | -1,049 | 15 | 1,259 | 877 | -4 | -4 | -5 | - | - | - | - |
Net cash used in operating activities | ||||||||||||||||||||
-26,250 | -61,240 | -43,681 | -32,929 | -50,381 | -32,820 | -29,010 | 71,394 | -32,426 | -22,754 | -23,411 | -20,088 | -17,418 | -13,347 | -11,832 | 390 | -7,136 | -6,668 | -2,848 | -1,392 | -1,619 |
Increase in restricted cash | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 1,000 | 55 |
Purchases of property and equipment | ||||||||||||||||||||
580 | 1,346 | 465 | 1,599 | 508 | 3,463 | 3,389 | 1,922 | 1,164 | 4,079 | 5,606 | 5,567 | 3,635 | 2,729 | 1,275 | 878 | 685 | 970 | 509 | 361 | 17 |
Net cash used in investing activities | ||||||||||||||||||||
-580 | -1,346 | -465 | -1,599 | -508 | -3,463 | -3,389 | -1,922 | -1,164 | -4,079 | -5,606 | -5,567 | -3,635 | -2,729 | -1,275 | -874 | -685 | -970 | -509 | -1,358 | -72 |
Cash flows from financing activities | ||||||||||||||||||||
Payments on capital lease obligation | ||||||||||||||||||||
- | - | - | - | - | 0 | 0 | 0 | 16 | 15 | 16 | 15 | 16 | 15 | 16 | 15 | 16 | - | - | - | - |
Proceeds from the exercise of share options | ||||||||||||||||||||
10 | 757 | 253 | 116 | 1,481 | 646 | 1,351 | 1,560 | 1,553 | 604 | 80 | 37 | 206 | - | - | - | - | - | - | - | - |
Net cash provided by financing activities | ||||||||||||||||||||
614 | 757 | 253 | -157 | 163,546 | 646 | 1,351 | 61,560 | 1,537 | 589 | 59 | 93,536 | 190 | 15 | 184 | 28,938 | -16 | 102,736 | 61,211 | 15 | 11,631 |
Effect of foreign exchange rates on cash, cash equivalents and restricted cash | ||||||||||||||||||||
6 | -15 | 2 | 30 | 97 | -28 | 110 | -88 | 43 | 285 | 30 | 31 | 57 | -115 | 173 | -86 | 14 | 82 | 407 | -447 | -27 |
Net increase (decrease) in cash, cash equivalents and restricted cash | ||||||||||||||||||||
-26,210 | -61,844 | -43,891 | -34,655 | 112,754 | -35,665 | -30,938 | 130,944 | -32,010 | -25,959 | -28,928 | 67,912 | -20,806 | -16,176 | -12,750 | 28,368 | -7,823 | 95,180 | 58,261 | -3,182 | 9,913 |
Supplemental disclosure of cash flow information: | ||||||||||||||||||||
Deferred follow-on offering costs in accounts payable and accrued expenses at period end | ||||||||||||||||||||
- | - | - | - | 280 | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - | - |
Cash paid for taxes, net of refunds | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 11 | 182 | 18 | - | - | - | - | - | - | - | - |
Property and equipment purchases in accounts payable and accrued expenses at period end | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | -1,568 | 11 | 2,976 | - | 556 | 854 | 185 | - | - | - | - |
Tenant improvements paid for by the landlord during the period | ||||||||||||||||||||
- | - | - | - | - | - | - | - | - | - | 408 | 1,284 | 1,082 | - | - | - | - | - | - | - | - |
At-The-Market Equity Program [Member] | ||||||||||||||||||||
Proceeds from issuance of ordinary shares, net of offering costs | ||||||||||||||||||||
604 | 0 | 0 | -273 | 162,065 | - | - | - | - | - | - | - | - | - | - | - | - | 0 | 0 | 0 | 11,631 |